Orphan nuclear receptor TLX regulates astrogenesis by modulating BMP signaling

Orphan nuclear receptor TLX regulates astrogenesis by modulating BMP signaling

Neural stem cells (NSCs) are self-renewing multipotent progenitors that generate both neurons and glia. The precise control of NSC behavior is fundamental to the architecture and function of the central nervous system. We previously demonstrated that the orphan nuclear receptor TLX is required for p...

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Bibliographic Details
Main Authors: Song eQin, Wenze eNiu, Nida eIqbal, Derek K. Smith, Chun-Li eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Neuroscience
Subjects:
Neural Stem Cells
Neurogenesis
nuclear receptor
TLX
astrogenesis
BMP-SMAD signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00074/full

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