Association of EV71 3C polymorphisms with clinical severity

Objectives: Enterovirus 71 (EV71) may cause neurological and fatal cases. EV71 3C plays an important role on viral replication and possess proteolysis activity. To delineate pathogenesis of EV71 virulence, we studied EV71 3C genetics, protease activity and correlated the results with clinical severi...

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Bibliographic Details
Main Authors: Hsuan-Yin Ma, Chun-Yi Lu, Kuo-Chien Tsao, Hsiu-Ming Shih, Ai-Ling Cheng, Li-Min Huang, Luan-Yin Chang
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118217300865