Dental Biofilm Microbiota Dysbiosis Is Associated With the Risk of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Dental Biofilm Microbiota Dysbiosis Is Associated With the Risk of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Acute graft-versus-host disease (aGVHD) is one of the major causes of death after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, aGVHD onset was linked to intestinal microbiota (IM) dysbiosis. However, other bacterial-rich gastrointestinal sites, such as the mouth, which h...

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Bibliographic Details
Main Authors: Vitor Heidrich, Julia S. Bruno, Franciele H. Knebel, Vinícius C. de Molla, Wanessa Miranda-Silva, Paula F. Asprino, Luciana Tucunduva, Vanderson Rocha, Yana Novis, Celso Arrais-Rodrigues, Eduardo R. Fregnani, Anamaria A. Camargo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
oral microbiota
supragingival plaque
microbiome dysbiosis
acute GVHD
allogeneic HSCT
bone marrow transplant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.692225/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.692225/full

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