Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease

Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease

Pathological synchronisation of beta frequency (12–35Hz) oscillations between the subthalamic nucleus (STN) and cerebral cortex is thought to contribute to motor impairment in Parkinson's disease (PD). For this cortico-subthalamic oscillatory drive to be mechanistically important, it must influ...

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Bibliographic Details
Main Authors: Andrew Sharott, Alessandro Gulberti, Wolfgang Hamel, Johannes A. Köppen, Alexander Münchau, Carsten Buhmann, Monika Pötter-Nerger, Manfred Westphal, Christian Gerloff, Christian K.E. Moll, Andreas K. Engel
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Subthalamic nucleus
Beta oscillations
Motor cortex
Neuronal synchronisation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118300019

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http://www.sciencedirect.com/science/article/pii/S0969996118300019

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