The Notch Signaling Pathway Is Balancing Type 1 Innate Lymphoid Cell Immune Functions

The Notch pathway is one of the canonical signaling pathways implicated in the development of various solid tumors. During carcinogenesis, the Notch pathway dysregulation induces tumor expression of Notch receptor ligands participating to escape the immune surveillance. The Notch pathway conditions...

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Bibliographic Details
Main Authors: Thibaut Perchet, Maxime Petit, Elena-Gaia Banchi, Sylvain Meunier, Ana Cumano, Rachel Golub
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01252/full