New Insights into the Runt Domain of RUNX2 in Melanoma Cell Proliferation and Migration

New Insights into the Runt Domain of RUNX2 in Melanoma Cell Proliferation and Migration

The mortality rate for malignant melanoma (MM) is very high, since it is highly invasive and resistant to chemotherapeutic treatments. The modulation of some transcription factors affects cellular processes in MM. In particular, a higher expression of the osteogenic master gene RUNX2 has been report...

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Bibliographic Details
Main Authors: Michela Deiana, Luca Dalle Carbonare, Michela Serena, Samuele Cheri, Francesca Parolini, Alberto Gandini, Giulia Marchetto, Giulio Innamorati, Marcello Manfredi, Emilio Marengo, Jessica Brandi, Daniela Cecconi, Antonio Mori, Maria Mihaela Mina, Franco Antoniazzi, Monica Mottes, Natascia Tiso, Giovanni Malerba, Donato Zipeto, Maria Teresa Valenti
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
RUNT
RUNX2
CRISPR/Cas9
melanoma
Online Access:https://www.mdpi.com/2073-4409/7/11/220

Internet

https://www.mdpi.com/2073-4409/7/11/220

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