Effects of N-Glycosylation on the Structure, Function, and Stability of a Plant-Made Fc-Fusion Anthrax Decoy Protein

Effects of N-Glycosylation on the Structure, Function, and Stability of a Plant-Made Fc-Fusion Anthrax Decoy Protein

Protein N-glycosylation is an important post-translational modification and has influences on a variety of biological processes at the cellular and molecular level, making glycosylation a major study aspect for glycoprotein-based therapeutics. To achieve a comprehensive understanding on how N-glycos...

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Bibliographic Details
Main Authors: Yongao Xiong, Kalimuthu Karuppanan, Austen Bernardi, Qiongyu Li, Vally Kommineni, Abhaya M. Dandekar, Carlito B. Lebrilla, Roland Faller, Karen A. McDonald, Somen Nandi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Plant Science
Subjects:
anthrax decoy protein
N-glycosylation
molecular simulation
protein stability
kinetics of protein binding
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2019.00768/full

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https://www.frontiersin.org/article/10.3389/fpls.2019.00768/full

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