Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma

Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma

<p>Abstract</p> <p>Background</p> <p>The histone deacetylase inhibitor vorinostat is a candidate radiosensitizer in locally advanced rectal cancer (LARC). Radiosensitivity is critically influenced by hypoxia; hence, it is important to evaluate the efficacy of potential...

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Bibliographic Details
Main Authors: Saelen Marie, Ree Anne, Kristian Alexandr, Fleten Karianne, Furre Torbjørn, Hektoen Helga, Flatmark Kjersti
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Radiation Oncology
Subjects:
Rectal cancer
Vorinostat
Fluoropyrimidine
Hypoxia
Radiation
Online Access:http://www.ro-journal.com/content/7/1/165

Internet

http://www.ro-journal.com/content/7/1/165

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