Perforin Acts as an Immune Regulator to Prevent the Progression of NAFLD

Perforin Acts as an Immune Regulator to Prevent the Progression of NAFLD

Non-alcoholic fatty liver disease (NAFLD) is one of the main causes of cirrhosis and major risk factors for hepatocellular carcinoma and liver-related death. Despite substantial clinical and basic research, the pathogenesis of obesity-related NAFLD remains poorly understood. In this study, we show t...

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Bibliographic Details
Main Authors: Qian Wang, Dehai Li, Jing Zhu, Mingyue Zhang, Hua Zhang, Guangchao Cao, Leqing Zhu, Qiping Shi, Jianlei Hao, Qiong Wen, Zonghua Liu, Hengwen Yang, Zhinan Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
perforin
NAFLD
CD4 T cells
IFN-γ
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00846/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00846/full

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