Hormonal therapy with estradiol and drospirenone improves endothelium-dependent vasodilation in the coronary bed of ovariectomized spontaneously hypertensive rats

Hormonal therapy with estradiol and drospirenone improves endothelium-dependent vasodilation in the coronary bed of ovariectomized spontaneously hypertensive rats

Drospirenone (DRSP) is a progestin with anti-aldosterone properties and it reduces blood pressure in hypertensive women. However, the effects of DRSP on endothelium-dependent coronary vasodilation have not been evaluated. This study investigated the effects of combined therapy with estrogen (E2) and...

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Bibliographic Details
Main Authors: M.V. Borgo, E.R.G. Claudio, F.B. Silva, W.G. Romero, S.A. Gouvea, M.R. Moysés, R.L. Santos, S.A. Almeida, P.L. Podratz, J.B. Graceli, G.R. Abreu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2016-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Menopause
Hypertension
Hormone therapy
Drospirenone
Coronary reactivity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100601&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100601&lng=en&tlng=en

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