ApoE4: an emerging therapeutic target for Alzheimer’s disease

ApoE4: an emerging therapeutic target for Alzheimer’s disease

Abstract Background The growing body of evidence indicating the heterogeneity of Alzheimer’s disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy, suggest that the development of a single magic cure suitable for all cases may not be possible. This calls for a s...

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Bibliographic Details
Main Authors: Mirna Safieh, Amos D. Korczyn, Daniel M. Michaelson
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medicine
Subjects:
Alzheimer’s disease
Apolipoprotein E4
apoE4 therapeutics
apoE4 lipidation
Anti-apoE4 antibodies
Human apoE-targeted replacement mice
Online Access:http://link.springer.com/article/10.1186/s12916-019-1299-4

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http://link.springer.com/article/10.1186/s12916-019-1299-4

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