Purification and functional characterization of two fibrinogenolytic enzymes from Bothrops alternatus venom

Two fibrinogenolytic enzymes, Bothrops alternatus metalloprotease isoform (BaltMP)-I and II, were purified from Bothrops alternatus venom using Diethylaminoethyl (DEAE) Sephacel, Sephadex G-75 and Heparin-Agarose column chromatography. Purified BaltMP-I and II ran as single protein bands on analytic...

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Bibliographic Details
Main Authors: J. O. Costa, C. B. Petric, A. Hamaguchi, M. I. Homsi-Brandeburgo, C. Z. Oliveira, A. M. Soares, F. Oliveira
Format: Article
Language:English
Published: SciELO 2007-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300007