Chromatin structure in telomere dynamics

Chromatin structure in telomere dynamics

The establishment of a specific nucleoprotein structure, the telomere, is required to ensure the protection of chromosome ends from being recognized as DNA damage sites. Telomere shortening below a critical length triggers a DNA damage response that leads to replicative senescence. In normal human s...

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Bibliographic Details
Main Authors: Alessandra eGalati, Emanuela eMicheli, Stefano eCacchione
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Oncology
Subjects:
Chromatin
Telomere
Telomere Shortening
Telomeric chromatin
telomere dynamics
Telomere epigenetics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00046/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00046/full

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