PLD3 epigenetic changes in the hippocampus of Alzheimer’s disease

PLD3 epigenetic changes in the hippocampus of Alzheimer’s disease

Abstract Background Whole-exome sequencing has revealed a rare missense variant in PLD3 gene (rs145999145) to be associated with late onset Alzheimer’s disease (AD). Nevertheless, the association remains controversial and little is known about the role of PLD3 in AD. Interestingly, PLD3 encodes a ph...

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Bibliographic Details
Main Authors: Idoia Blanco-Luquin, Miren Altuna, Javier Sánchez-Ruiz de Gordoa, Amaya Urdánoz-Casado, Miren Roldán, María Cámara, Victoria Zelaya, María Elena Erro, Carmen Echavarri, Maite Mendioroz
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Clinical Epigenetics
Subjects:
PLD3
Alzheimer’s disease
Epigenetics
DNA methylation
Gene and protein expression
Hippocampus
Online Access:http://link.springer.com/article/10.1186/s13148-018-0547-3

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http://link.springer.com/article/10.1186/s13148-018-0547-3

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