Disparity of outcomes: the limits of modeling amyotrophic lateral sclerosis in murine models and translating results clinically

Amyotrophic lateral sclerosis (ALS) is a devastatingly progressive neurodegenerative disorder with multiple underlying etiological factors contributing to disease pathogenesis. Despite intensive research efforts and therapeutic development, disease presentation in ALS remains largely intractable to...

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Bibliographic Details
Main Authors: Pierre Zwiegers, Christopher A Shaw
Format: Article
Language:English
Published: Biogenic Press 2015-08-01
Series:Journal of Controversies in Biomedical Research
Subjects:
Online Access:https://jcbmr.com/index.php/jcbmr/article/view/3