What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows

The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points in the experimental process, and normalization strategies are crucial to attempt to overcome...

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Bibliographic Details
Main Authors: Matthew B. O’Rourke, Stephanie E. L. Town, Penelope V. Dalla, Fiona Bicknell, Naomi Koh Belic, Jake P. Violi, Joel R. Steele, Matthew P. Padula
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/7/3/29