Cigarette smoking decreases global microRNA expression in human alveolar macrophages.

Cigarette smoking decreases global microRNA expression in human alveolar macrophages.

Human alveolar macrophages are critical components of the innate immune system. Cigarette smoking-induced changes in alveolar macrophage gene expression are linked to reduced resistance to pulmonary infections and to the development of emphysema/COPD. We hypothesized that microRNAs (miRNAs) could co...

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Bibliographic Details
Main Authors: Joel W Graff, Linda S Powers, Anne M Dickson, Jongkwang Kim, Anna C Reisetter, Ihab H Hassan, Karol Kremens, Thomas J Gross, Mary E Wilson, Martha M Monick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430644?pdf=render

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http://europepmc.org/articles/PMC3430644?pdf=render

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