HNF-4α inhibits hepatocellular carcinoma cell proliferation through mir-122-adam17 pathway.

Hepatocellular carcinoma (HCC) is one of the most common human cancers, its prevalence and severity need us to discover novel early diagnostic biomarkers and new therapeutic strategies. MicroRNA-122 is the most abundant microRNA in the liver, and acts as a tumor suppressor and represses HCC developm...

Full description

Bibliographic Details
Main Authors: Guang Yang, Min Zhang, Yawei Zhao, Yue Pan, Mujie Kan, Jing Li, Kan He, Xuewen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230450