Stabilization of partially folded states in protein folding/misfolding transitions by hydrostatic pressure
In the last few years, hydrostatic pressure has been extensively used in the study of both protein folding and misfolding/aggregation. Compared to other chemical or physical denaturing agents, a unique feature of pressure is its ability to induce subtle changes in protein conformation, which allow t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2005-08-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000800009 |