The evolution of genome-scale models of cancer metabolism

The importance of metabolism in cancer is becoming increasingly apparent with the identification of metabolic enzyme mutations and the growing awareness of the influence of metabolism on signaling, epigenetic markers, and transcription. However, the complexity of these processes has challenged our a...

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Bibliographic Details
Main Authors: Nathan E Lewis, Alyaa M Abdel-Haleem
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00237/full