Association of Variants in PLD1, 3p24.1, and 10q11.21 Regions With Hirschsprung’s Disease in Han Chinese Population

Association of Variants in PLD1, 3p24.1, and 10q11.21 Regions With Hirschsprung’s Disease in Han Chinese Population

Background and Aims: Hirschsprung’s disease (HSCR) is a rare genetically heterogeneous congenital disorder. A recent study based on whole genome sequencing demonstrated that common variants at four novel loci, which contained two intronic variants on CASQ2 and PLD1, and intergenic variants located b...

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Bibliographic Details
Main Authors: Wei-Bo Niu, Mei-Rong Bai, Huan-Lei Song, Yan-Jiao Lu, Wen-Jie Wu, Yi-Ming Gong, Xian-Xian Yu, Zhi-Liang Wei, Wen-Wen Yu, Bei-Lin Gu, Wei Cai, Xun Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Genetics
Subjects:
association
Hirschsprung’s disease
case-control study
single nucleotide polymorphisms
Han Chinese population
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00738/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00738/full

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