Mucin-1 aptamer-armed superparamagnetic iron oxide nanoparticles for targeted delivery of doxorubicin to breast cancer cells

Introduction: Superparamagnetic iron oxide nanoparticles (SPIONs) can be functionalized with various agents (e.g., targeting and therapeutic agents) and used for targeted imaging/therapy of cancer. In the present study, we engineered doxorubicin (DOX)-conjugated anti-mucin-1 (MUC-1) aptamer (Ap)-arm...

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Bibliographic Details
Main Authors: Ayuob Aghanejad, Hiwa Babamiri, Khosro Adibkia, Jaleh Barar, Yadollah Omidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-03-01
Series:BioImpacts
Subjects:
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-8-117.pdf