Prognostic Significance of <i>O</i>-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer

Prognostic Significance of <i>O</i>-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer

Predictive metabolic biomarkers for the recurrent luminal breast cancer (BC) with hormone receptor (HR)-positive and human epidermal growth factor receptor type 2 (HER2)-negative are lacking. High levels of <i>O</i>-GlcNAcylation (<i>O</i>-GlcNAc) and pyruvate kinase isoenzym...

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Bibliographic Details
Main Authors: Wen-Ling Kuo, Lin-Lu Tseng, Che-Chang Chang, Chih-Jung Chen, Mei-Ling Cheng, Hsin-Hung Cheng, Meng-Jen Wu, Yu-Lun Chen, Ruei-Ting Chang, Hsiang-Yu Tang, Yong-Chen Hsu, Wen-Jye Lin, Cheng-Yuan Kao, Wen-Ping Hsieh, Hsing-Jien Kung, Wen-Ching Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Diagnostics
Subjects:
<i>O</i>-GlcNAc
PKM2
HR<sup>+</sup>/HER2<sup>−</sup> luminal breast cancer
metabolism
prognosis
Online Access:https://www.mdpi.com/2075-4418/11/8/1460

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https://www.mdpi.com/2075-4418/11/8/1460

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