Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising tools for treatment of several neurological and neurodegenerative diseases. MSCs release abundant extracellular vesicles (EVs) containing a variety of biomolecules, including mRNAs, miRNAs, and proteins. We hypothesize...

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Bibliographic Details
Main Authors: Victor Bodart-Santos, Luiza R. P. de Carvalho, Mariana A. de Godoy, André F. Batista, Leonardo M. Saraiva, Luize G. Lima, Carla Andreia Abreu, Fernanda G. De Felice, Antonio Galina, Rosalia Mendez-Otero, Sergio T. Ferreira
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Stem Cell Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13287-019-1432-5

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http://link.springer.com/article/10.1186/s13287-019-1432-5

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