Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer

Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer

Hypoxia is a common feature of solid tumors. As transcription factors, hypoxia-inducible factors (HIFs) are the master regulators of the hypoxic microenvironment; their target genes function in tumorigenesis and tumor development. Intriguingly, both yes-associated protein (YAP) and its paralog trans...

Full description

Bibliographic Details
Main Authors: Chenxi Zhao, Chenming Zeng, Song Ye, Xiaoyang Dai, Qiaojun He, Bo Yang, Hong Zhu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
YAP
TAZ
HIFs
Hypoxia
Solid tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519308214

Internet

http://www.sciencedirect.com/science/article/pii/S2211383519308214

Similar Items