Molecular mechanisms of photosensitization induced by drugs XIV: Two different behaviours in the photochemistry and photosensitization of antibacterials containing a fluoroquinolone like chromophore

This paper deals with the photosensitizing activity of FLQs towards two different biosubstrates, membrane and DNA. The in vitro phototoxic activity of these drugs vs. DNA presents peculiar features with respect to that vs. membranes, probably due to a specific binding of the drugs to the double heli...

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Bibliographic Details
Main Authors: G. De Guidi, S. Giuffrida, S. Monti, P. S. Pisu, S. Sortino, L. L. Costanzo
Format: Article
Language:English
Published: Hindawi Limited 1999-01-01
Series:International Journal of Photoenergy
Online Access:http://dx.doi.org/10.1155/S1110662X99000033