Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels.

Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels.

The prognosis of hepatocellular carcinoma patients is usually poor, the size of tumors being a limiting factor for surgical treatments. Present results suggest that the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, proliferating activity and malignancy of liver tumors. Mic...

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Bibliographic Details
Main Authors: Natalia Sacilotto, Josefa Castillo, Ángela L Riffo-Campos, Juana M Flores, Olivia Hibbitt, Richard Wade-Martins, Carlos López, M Isabel Rodrigo, Luis Franco, Gerardo López-Rodas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4498802?pdf=render

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http://europepmc.org/articles/PMC4498802?pdf=render

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