Evolution of phage with chemically ambiguous proteomes

<p>Abstract</p> <p>Background</p> <p>The widespread introduction of amino acid substitutions into organismal proteomes has occurred during natural evolution, but has been difficult to achieve by directed evolution. The adaptation of the translation apparatus represents...

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Bibliographic Details
Main Authors: Bull James J, Bacher Jamie M, Ellington Andrew D
Format: Article
Language:English
Published: BMC 2003-12-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/3/24