Use of cDNA tiling arrays for identifying protein interactions selected by in vitro display technologies.

In vitro display technologies such as mRNA display are powerful screening tools for protein interaction analysis, but the final cloning and sequencing processes represent a bottleneck, resulting in many false negatives. Here we describe an application of tiling array technology to identify specifica...

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Bibliographic Details
Main Authors: Kenichi Horisawa, Nobuhide Doi, Hiroshi Yanagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2241667?pdf=render