Quantification of the <em>Lamin A/C</em> Transcript Variants in Cancer Cell Lines by Targeted Absolute Quantitative Proteomics and Correlation with mRNA Expression

Quantification of the <em>Lamin A/C</em> Transcript Variants in Cancer Cell Lines by Targeted Absolute Quantitative Proteomics and Correlation with mRNA Expression

<i>Lamin A/C</i> proteins have key roles in nuclear structural integrity and chromosomal stability. <i>Lamin A/C</i> cumulative protein expression of all variants is reported by semi-quantitative Western blotting. To date, there have not been specific antibodies for the indiv...

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Bibliographic Details
Main Authors: Wedad Saeed Al-Qahtani, Mai Abduljabbar, Entissar S. AlSuhaibani, Anas Abdel Rahman, Ahmad Aljada
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
lamin A
lamin C
lamin AΔ10
lamin AΔ50 (Progerin)
LC–MS/MS
MCF7
U937
Online Access:https://www.mdpi.com/1422-0067/20/8/1902

Internet

https://www.mdpi.com/1422-0067/20/8/1902

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