Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer

Cilia are antenna-like structures present in many vertebrate cells. These organelles detect extracellular cues, transduce signals into the cell, and play an essential role in ensuring correct cell proliferation, migration, and differentiation in a spatiotemporal manner. Not surprisingly, dysregulati...

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Bibliographic Details
Main Authors: Takashi Shiromizu, Mizuki Yuge, Kousuke Kasahara, Daishi Yamakawa, Takaaki Matsui, Yasumasa Bessho, Masaki Inagaki, Yuhei Nishimura
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitin–proteasome pathway
cilia
ciliogenesis
differentiation
proliferation
ciliopathy
Online Access:https://www.mdpi.com/1422-0067/21/17/5962

Internet

https://www.mdpi.com/1422-0067/21/17/5962

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