Klotho Ameliorates Chemically Induced Endoplasmic Reticulum (ER) Stress Signaling

Klotho Ameliorates Chemically Induced Endoplasmic Reticulum (ER) Stress Signaling

Background: Both endoplasmic reticulum (ER) stress, a fundamental cell response associated with stress-initiated unfolded protein response (UPR), and loss of Klotho, an anti-aging hormone linked to NF-κB-induced inflammation, occur in chronic metabolic diseases such as obesity and type 2 di...

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Bibliographic Details
Main Authors: Srijita Banerjee, Yanhua Zhao, Partha S. Sarkar, Kevin P. Rosenblatt, Ronald G. Tilton, Sanjeev Choudhary
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tunicamycin
Unfolded protein response
Klotho
ER stress
Thapsigargin
Online Access:http://www.karger.com/Article/FullText/350085

Internet

http://www.karger.com/Article/FullText/350085

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