Multifactor dimensionality reduction: An analysis strategy for modelling and detecting gene - gene interactions in human genetics and pharmacogenomics studies

<p>Abstract</p> <p>The detection of gene - gene and gene - environment interactions associated with complex human disease or pharmacogenomic endpoints is a difficult challenge for human geneticists. Unlike rare, Mendelian diseases that are associated with a single gene, most common...

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Bibliographic Details
Main Authors: Motsinger Alison A, Ritchie Marylyn D
Format: Article
Language:English
Published: BMC 2006-03-01
Series:Human Genomics
Subjects:
Online Access:http://www.humgenomics.com/content/2/5/318