Dual Mechanisms of Metabolism and Gene Expression of the CCRF-CEM Leukemia Cells under Glucocorticoid Treatment

Dual Mechanisms of Metabolism and Gene Expression of the CCRF-CEM Leukemia Cells under Glucocorticoid Treatment

Background: Glucocorticoids play an essential part in anti-leukemic therapies, but resistance is a crucial event for the prognosis of the disease. Glucocorticoids influence the metabolic properties of leukemic cells. The inherent plasticity of clinically evolving cancer cells justifies the character...

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Bibliographic Details
Main Authors: George I. Lambrou, Theodoros Karakonstantakis, Spiros Vlahopoulos, Apostolos Zaravinos
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
prednisolone
flow cytometry
proliferation
differential gene expression
apoptosis
invasion
Online Access:https://www.mdpi.com/1422-0067/22/11/5889

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https://www.mdpi.com/1422-0067/22/11/5889

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