Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages.

Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages.

Human disease caused by highly pathogenic avian influenza (HPAI) H5N1 can lead to a rapidly progressive viral pneumonia leading to acute respiratory distress syndrome. There is increasing evidence from clinical, animal models and in vitro data, which suggests a role for virus-induced cytokine dysreg...

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Bibliographic Details
Main Authors: Suki M Y Lee, Jennifer L Gardy, C Y Cheung, Timothy K W Cheung, Kenrie P Y Hui, Nancy Y Ip, Y Guan, Robert E W Hancock, J S Malik Peiris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2788213?pdf=render

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http://europepmc.org/articles/PMC2788213?pdf=render

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