High-resolution 3D imaging of osteocytes and computational modelling in mechanobiology: insights on bone development, ageing, health and disease

Osteocytes are involved in mechanosensation and mechanotransduction in bone and hence, are key to bone adaptation in response to development, ageing and disease. Thus, detailed knowledge of the three-dimensional (3D) structure of the osteocyte network (ON) and the surrounding lacuno-canalicular netw...

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Bibliographic Details
Main Authors: PM Goggin, KC Zygalakis, ROC Oreffo, P Schneider
Format: Article
Language:English
Published: AO Research Institute Davos 2016-05-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol031/pdf/v031a18.pdf