Degradation of endocannabinoids in chronic migraine and medication overuse headache

Degradation of endocannabinoids in chronic migraine and medication overuse headache

Chronic migraine (CM) is frequently associated with medication overuse headache (MOH). The endocannabinoid system plays a role in modulating pain including headache and is involved in the common neurobiological mechanism underlying drug addiction and reward system. Anandamide (AEA) and 2-arachidonoy...

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Bibliographic Details
Main Authors:	L.M. Cupini, C. Costa, P. Sarchielli, M. Bari, N. Battista, P. Eusebi, P. Calabresi, M. Maccarrone
Format:	Article
Language:	English
Published:	Elsevier 2008-05-01
Series:	Neurobiology of Disease
Subjects:	Endocannabinoids Episodic migraine Chronic migraine Medication overuse headache
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996108000065

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