A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.

We have previously shown that genetic variability in CNR1 is associated with low HDL dyslipidemia in a multigenerational obesity study cohort of Northern European descent (209 families, median  = 10 individuals per pedigree). In order to assess the impact of CNR1 variability on the development of dy...

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Bibliographic Details
Main Authors: Qiping Feng, Lan Jiang, Richard L Berg, Melissa Antonik, Erin MacKinney, Jennifer Gunnell-Santoro, Catherine A McCarty, Russell A Wilke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3013130?pdf=render