Detection of ZrO2 Nanoparticles in Lung Tissue Sections by Time-of-Flight Secondary Ion Mass Spectrometry and Ion Beam Microscopy

Detection of ZrO2 Nanoparticles in Lung Tissue Sections by Time-of-Flight Secondary Ion Mass Spectrometry and Ion Beam Microscopy

The increasing use of nanoparticles (NP) in commercial products requires elaborated techniques to detect NP in the tissue of exposed organisms. However, due to the low amount of material, the detection and exact localization of NP within tissue sections is demanding. In this respect, Time-of-Flight...

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Bibliographic Details
Main Authors: Lothar Veith, Julia Böttner, Antje Vennemann, Daniel Breitenstein, Carsten Engelhard, Jan Meijer, Irina Estrela-Lopis, Martin Wiemann, Birgit Hagenhoff
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Nanomaterials
Subjects:
ToF-SIMS
ion beam microscopy
particle-induced X-ray emission
ZrO2 nanoparticles
lung tissue
instillation
toxicity
gas cluster ion beam
delayed extraction
Online Access:http://www.mdpi.com/2079-4991/8/1/44

Internet

http://www.mdpi.com/2079-4991/8/1/44

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