Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development

Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development

Abstract Immunomodulation with anti‐TNF‐α is highly effective in the treatment of various immune‐mediated inflammatory diseases, including hidradenitis suppurativa (HS). However, this may be responsible for unexpected paradoxical psoriasiform reactions. The pathogenic mechanisms underlying the induc...

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Bibliographic Details
Main Authors: Luca Fania, Martina Morelli, Claudia Scarponi, Laura Mercurio, Fernanda Scopelliti, Caterina Cattani, Giovanni Luca Scaglione, Tiziano Tonanzi, Maria Antonietta Pilla, Gianluca Pagnanelli, Cinzia Mazzanti, Giampiero Girolomoni, Andrea Cavani, Stefania Madonna, Cristina Albanesi
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:The Journal of Pathology: Clinical Research
Subjects:
psoriasis
hidradenitis suppurativa
anti‐TNF‐α therapy
paradoxical psoriasis
skin inflammation
innate immunity
Online Access:https://doi.org/10.1002/cjp2.147

Internet

https://doi.org/10.1002/cjp2.147

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