Circulating 20S proteasome is independently associated with abdominal muscle mass in hemodialysis patients.

Protein-energy wasting is highly prevalent in hemodialysis patients, and it contributes to patient morbidity and mortality. The ubiquitin-proteasome system is the major pathway for intracellular protein degradation and it is involved in the regulation of basic cellular processes. However, the role o...

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Bibliographic Details
Main Authors: Hirotaka Fukasawa, Mai Kaneko, Hiroki Niwa, Takashi Matsuyama, Hideo Yasuda, Hiromichi Kumagai, Ryuichi Furuya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372611?pdf=render