Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties.

Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties.

Induction of adult rat bone marrow mesenchymal stem cells (MSC) by means of chemical compounds (beta-mercaptoethanol, dimethyl sulfoxide and butylated hydroxyanizole) has been proposed to lead to neuronal transdifferentiation, and this protocol has been broadly used by several laboratories worldwide...

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Bibliographic Details
Main Authors: Gabriela F Barnabé, Telma T Schwindt, Maria E Calcagnotto, Fabiana L Motta, Gilberto Martinez, Allan C de Oliveira, Leda M N Keim, Vânia D'Almeida, Rosália Mendez-Otero, Luiz E Mello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2667250?pdf=render

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http://europepmc.org/articles/PMC2667250?pdf=render

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