Breast tumor cell hybrids form spontaneously in vivo and contribute to breast tumor metastases

Cancer cell fusion was suggested as a mechanism of metastasis about a century ago. Since then, many additional modes of material transfer (i.e., tunneling nanotubes, and exosomes) to generate cell hybrids have been identified. However, studies documenting spontaneous tumor hybrid formation in vivo a...

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Bibliographic Details
Main Authors: Casey A. Chitwood, Claire Dietzsch, Gabriel Jacobs, Tanner McArdle, Brian T. Freeman, Annanya Banga, Felicite K. Noubissi, Brenda M. Ogle
Format: Article
Language:English
Published: AIP Publishing LLC 2018-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5024744