Characterization of an ETV6-NTRK3 rearrangement with unusual, but highly significant FISH signal pattern in a secretory carcinoma of the salivary gland: a case report

Characterization of an ETV6-NTRK3 rearrangement with unusual, but highly significant FISH signal pattern in a secretory carcinoma of the salivary gland: a case report

Abstract Background Fusions of neurotrophic tropomyosin receptor kinase genes NTRK1, NTRK2 and NTRK3 with various partner genes occur in both common and rare tumours and are of paramount predictive value due to the availability of very effective pan-Trk inhibitors like Larotrectinib and Entrectinib....

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Bibliographic Details
Main Authors: Florian Wagner, Ralf Greim, Kathrin Krebs, Finn Luebben, Arno Dimmler
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Diagnostic Pathology
Subjects:
ETV6-NTRK3 fusion
Salivary gland
Secretory carcinoma
NTRK3 break apart FISH
Case report
Online Access:https://doi.org/10.1186/s13000-021-01133-z

Internet

https://doi.org/10.1186/s13000-021-01133-z

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