Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section

Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section

Abstract Background Rats are a widely accepted preclinical model for evaluating intervertebral disc (IVD) degeneration and regeneration. IVD morphology is commonly assessed using histology, which forms the foundation for quantifying the state of IVD degeneration. IVD degeneration severity is evaluat...

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Bibliographic Details
Main Authors: Alon Lai, Jennifer Gansau, Sarah E. Gullbrand, James Crowley, Carla Cunha, Stefan Dudli, Julie B. Engiles, Marion Fusellier, Raquel M. Goncalves, Daisuke Nakashima, Jeffrey Okewunmi, Matthew Pelletier, Steven M. Presciutti, Jordy Schol, Yoshiki Takeoka, Sidong Yang, Takashi Yurube, Yejia Zhang, James C. Iatridis
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:JOR Spine
Subjects:
histology
histology grading scale
histopathology
intervertebral disc degeneration
intervertebral disc regeneration
rat model
Online Access:https://doi.org/10.1002/jsp2.1150

Internet

https://doi.org/10.1002/jsp2.1150

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