Acetylated and Methylated β-Cyclodextrins as Viable Soluble Supports for the Synthesis of Short 2′-Oligodeoxyribo-nucleotides in Solution

Acetylated and Methylated β-Cyclodextrins as Viable Soluble Supports for the Synthesis of Short 2′-Oligodeoxyribo-nucleotides in Solution

Novel soluble supports for oligonucleotide synthesis 11a–c have been prepared by immobilizing a 5′-O-protected 3′-O-(hex-5-ynoyl)thymidine (6 or 7) to peracetylated or permethylated 6-deoxy-6-azido-β-cyclodextrins 10a or 10b by Cu(I)-promoted 1,...

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Bibliographic Details
Main Authors: Harri Lönnberg, Pasi Virta, Vyacheslav Kungurtsev, Alejandro Gimenez Molina
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Molecules
Subjects:
cyclodextrin
oligonucleotides
phosphoramidites
soluble support
synthesis
Online Access:http://www.mdpi.com/1420-3049/17/10/12102

Internet

http://www.mdpi.com/1420-3049/17/10/12102

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