Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

<p>Abstract</p> <p>Parkinson's disease (PD) is histologically well defined by its characteristic degeneration of dopaminergic neurons in the <it>substantia nigra pars compacta</it>. Remarkably, divergent PD-related mutations can generate comparable brain region spe...

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Bibliographic Details
Main Authors: Zabel Claus, Shen Jie, Koppelstaetter Andrea, Nebrich Grit, Kitada Tohru, Diedrich Madeleine, Klose Joachim, Mao Lei
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Proteome Science
Subjects:
Parkinson's disease
mitophagy
proteomics
PINK1
2DE
Online Access:http://www.proteomesci.com/content/9/1/59

Internet

http://www.proteomesci.com/content/9/1/59

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