IL-17A Induces Pro-Inflammatory Cytokines Production in Macrophages via MAPKinases, NF-κB and AP-1

IL-17A Induces Pro-Inflammatory Cytokines Production in Macrophages via MAPKinases, NF-κB and AP-1

Background: Interleukin (IL)-17A, a newly identified cytokine, may participate in the transition of a stable plaque into an unstable plaque. Macrophages play a critical role in the destabilization of atherosclerotic plaque. Methods: RAW 264.7 cells were stimulated with IL-17A. The mRNA expression of...

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Bibliographic Details
Main Authors: Jian Chen, Meng-yang Liao, Xing-li Gao, Qi Zhong, Ting-ting Tang, Xian Yu, Yu-hua Liao, Xiang Cheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Inflammatory cytokines
Macrophages
Interleukin 17A
Online Access:http://www.karger.com/Article/FullText/354525

Internet

http://www.karger.com/Article/FullText/354525

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