Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

<p>Abstract</p> <p>Background</p> <p>Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological feat...

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Bibliographic Details
Main Authors: Zhang Dake, Dong Peiling, Zhang Ke, Deng Libin, Bach Christian, Chen Wei, Li Feifei, Protzer Ulrike, Ding Huiguo, Zeng Changqing
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Microbiology
Subjects:
HBV
Deletion
PreS
Chronic hepatitis
Antiviral therapy
Nucleotide analog
Online Access:http://www.biomedcentral.com/1471-2180/12/307

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http://www.biomedcentral.com/1471-2180/12/307

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