Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

The Amyloid-β (Aβ)-induced impairment of hippocampal synaptic plasticity is an underlying mechanism of memory loss in the early stages of Alzheimer's disease (AD) in human and mouse models. The inhibition of the calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation pla...

Full description

Bibliographic Details
Main Authors: Lian-Feng Zhang, Fei-Fei Guan, Xu Zhang, Li Zhang, Ya-Jun Yang, Dong-Mei Wang
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:International Journal of Molecular Sciences
Subjects:
Naringin
Alzheimer’s disease
APPswe/PS1dE9 mice
CaMKII
Online Access:http://www.mdpi.com/1422-0067/14/3/5576

Internet

http://www.mdpi.com/1422-0067/14/3/5576

Similar Items